I have tried running the game using Tridef, as usual the best result is to run the default profile (which has a profile menu you can tweak, unlike the other preset profiles which are locked).
Since fullscreen mode isn't really a true exclusive fullscreen mode, HD3D and custom resolutions don't kick in, side by side works though.
I have only played a couple scenes yet.
Here are my settings
Performance > power 3D > off (real 3D here, power3D is broken in this game anyways)
Performance > 3D texture copy > diabled
Profile > 3D object detection > shader analyser > ticked
That's about it, nothing else has any effect.
The game looks good most of the time, but shadow glitches appear very often.
Graphics glitches :
-on the game's main menu, the light rays appear at the wrong depth.
-projected shadows are off, some scenes are worse than others. the 3D scene settings (ratio between depth and pop-out) appears to scale the shadows. You can reduce it by an acceptable amount if you set the game far into pop-out.
-water reflections are broken (intro sequence, haven't seen further in the game)
-weird lens flare glitch when a light source touches the edge of the screen
Gameplay glitch : the entire interface is at screen depth (it's a simple 2D HUD), it doesn't project in depth near the objects over which you put your mouse cursor.
Framerate is really bad and it appears that setting the game to low quaity or awesome has zero effect (Tridef's famous CPU bottlenecks)