The GoG staff are currently looking into the issues with the latest patch (4.1.1) that was released on GoG.com earlier in December.
Players have reported several issues, and the most prominent ones seem to be with loading scenes and savegames, getting stuck at the black loading screen with audio still playing (or similar).
The staff over on GoG have asked us to tell anyone that are having problems with the patch, to write their support department.
In the issue report, please add a short description of the issue and attach your DxDiag info as well as the Unity player log for the game.
For information on how to obtain these files, please see the following section of our FAQ.
GoG contact information and forms can be found through their website here.
Thanks for your patience and understanding while we try to figure out what the cause of these issues are.
We will update this topic further as we get more information from the GoG staff.